Gut Research is a research group that is part of the Tytgat Institute for Liver and Intestinal Research, and the Dept. of Gastroenterology at the Academic Medical Center (AMC) in Amsterdam. We are a group of research fellows, master students, basic researchers and physicians that hope to bridge basic research and drug development. Click on the link for more information about the Tytgat Institute or GutResearch.
Inflammation is a hallmark of atherosclerosis and correlates with plaque progression, severity and stability. The abundance of inflammatory cells, and more specifically macrophages often as lipid laden foam cells, associates with key features of plaque instability and circulating inflammatory markers are good predictors of clinical disease outcome. Click on the link for more information about Medical Biochemistry.
GSK is a global-healtcare company and develops several medicines to treat acute and chronic diseases. Rab Prinjha leads the Epinova epigenetics Discovery Performance Unit in the Immuno-Inflammation therapy area (II-TA). Click on the link for more information about GSK.
The department of Clinical Genetics is dedicated to fast, reliable, high quality laboratory diagnostics and genetic counseling. Therefore evaluation and implementation of innovative genetic laboratory diagnostic strategies and of new approaches in genetic counseling are regarded as main issues of research. Click on the link for more information about Clinical Genetics.
“I believe the most exciting aspect of Epimac is the collaborative nature of the project, where I am capable of using the strengths from the academic hospital as well as the pharmaceutical industry in elucidating the role of the epigenome in the pathogenesis of inflammatory bowel diseases.”
“The central role of macrophages in modulating human disease is well established. Emerging evidence of innate memory and macrophage plasticity requiring epigenetic processes makes Epimac an incredibly timely and exciting collaboration.”