Defining tissue- and disease-associated macrophages using a 1 transcriptome-based classification model
Macrophages are heterogeneous multifunctional leukocytes which are regulated in a tissue- and disease-specific context. Many different studies have been published using in vitro macrophage models to study disease. Here, we aggregated public expression data to define consensus expression profiles for eight commonly-used in vitro macrophage models. Altogether, we observed well-known but also novel markers for different macrophage subtypes.